Dyson, Freeman J. Origins of Life. 2nd. ed. Cambridge: Cambridge University Press, 1999. ISBN 0-521-62668-4.
The years which followed Freeman Dyson's 1985 Tarner lectures, published in the first edition of Origins of Life that year, saw tremendous progress in molecular biology, including the determination of the complete nucleotide sequences of organisms ranging from E. coli to H. sapiens, and a variety of evidence indicating the importance of Archaea and the deep, hot biosphere to theories of the origin of life. In this extensively revised second edition, Dyson incorporates subsequent work relevant to his double-origin (metabolism first, replication later) hypothesis. It's perhaps indicative of how difficult the problem of the origin of life is that none of the multitude of experiments done in the almost 20 years since Dyson's original lectures has substantially confirmed or denied his theory nor answered any of the explicit questions he posed as challenges to experimenters.

March 2004 Permalink